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PTI-129, a once-daily, oral small molecule demonstrates the potential to reduce viral protein production in host cells.
June 1, 2020
By: Contract Pharma
Contract Pharma Staff
Proteostasis Therapeutics, Inc., a clinical stage biopharma company developing therapies to treat cystic fibrosis (CF), announced results from in vitro studies evaluating the use of PTI-129 as a treatment for COVID-19. PTI-129 is a preclinical, once-daily, oral small molecule originally designed to treat protein misfolding disorders involving the unfolded protein response (UPR). Upon infection, coronaviruses hijack the host cell endoplasmic reticulum (ER) to quickly produce a larger quantity of...
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